Dr Martin Mpe works as a private cardiologist at Mediclinic Heart Hospital in Pretoria and Netcare Pholoso Hospital in Polokwane. He is also a session cardiologist and acting HOD of the
Heart Unit at No. 1 Military Hospital in Thaba-Tshwane where he assists in interventional  cardiology and cardiac pacing, including cardiac resynchronization therapy and ICD implants.

Membership of associations include:

• Chairperson of the Board of SA Heart Association
• Chairperson of the Social and Ethics Committee of the SA Heart Board
• Immediate past-President of the Heart Failure Society of South Africa
• Advisory board member and immediate past-President of the SA Hypertension Society
• Previous member and past Chairperson of the Aero-Medical Committee of the SA Civil Aviation Authority